Genetic Algorithm (GA) as Optimization Technique

Genetic Algorithm (GA) as Optimization Technique Preference learning (or preference elicitation) is a critical problem in many scientific fields, such as decision theory [1,2], economics [3,4], logistic [ref] and database [5]. When modeling user preference, researchers often model the preferences as a solution to an optimization problem which maximizes some utility function. In reality, however, we are not a-priori given a utility but have only access to a finite historical user choice data. Therefore, the passive preference learning problem, that is, how to learn user preferences using her historical choice data, has gained a lot of attention in recent years. When dealing with preference learning, it is often assumed that user preference over the values of each attribute is independent of the values of other attributes. However, this assumption is not a sound in many world scenarios. For example, as it is shown in Fig. 1 for cloth shopping problem, one might choose the color of her shoes depending on the color of dress she will buy, i.e. her preference over shoes color is conditioned by the available dresses. More formally, we say the preferences induced by the users behavior are intrinsically related to textit{conditional preferential independence}, a key notion in multi-attribute decision theory[20]. Conditional preference networks (CP-nets) have been proposed for such problems [4] and have received a great deal of attention due to the compact and natural representation of ordinal preferences in multi-attribute domains [8-12, 17-19,22]. Briefly, a CP-net, fig. 1, is a digraph, whose nodes correspond to alternative attributes and edges correspond to the dependency between nodes and each node is annotated with a conditional preference table which describe the preferences over that particular attribute (chapter 3). It is sometimes claimed that CP-nets are `easy to elicit [16]. That is, we first explain CP-nets to the user, and then ask her to write down the CP-net that best describes her decision-making process [18,30]. However, it has been shown that when facing the choices, people often act differently from what they described previously as their preferences [39,40,97,103]. As an example, Kamishima and Akaho [53] point out that when customers were asked to rank ten sushi items and then later to assign rating scores to the same items, in 68% of the cases, the ordering implied by the ratings did not agree with the ranking elicited directly only minutes before. Based on these experiments, several CP-net learning algorithms have been developed depend on the users choice data. Some algorithms work on the historical choice data [23,64], a process known as passive learning. Others actively offer solutions in an attempt to learn the users preferences as they choose [23,29,47,58].   The work of this paper falls into the category of passive learning, in which the learner uses the recorded users choices and then fits a CP-net model to the observed data. Formally, we collect the set of samples $S = {o_i succ o_i}$, where   $o_i succ o_i$ means that the user strictly prefers outcome $o_i$ over outcome $o_i$ and then find a model $N$ that can best describe $S$. Such set of samples may be gathered, for instance, by observing online users choices. Table1 shows the number of binary CP-nets up to 7 nodes, i.e. each outcome consists of 7 attributes [A250110]. From the values, it is evident that, even for a small number of attributes, finding the best CP-net is not a trivial task due to the huge size of the search space. textbf{inja np-completo begoo.} To the best of our knowledge, there is no existing approach that can perform well on problem with more than 7 attributes hence they are not practical when facing real world problems, in which the alternatives usually consist of tens or even hundreds of attributes. Another problem that rises when learning preferences from human subjects is the possibility of noise or comparison data that are ultimately inconsistent in the chose data-set $S$. While noise is results of the observation of the users behavior,   inconsistency is the result of randomicity of the users behaviors; that   is, the transitive closure of data-set may result in a cycle in which some outcome $o$ is seen to be preferred to itself. The objective of most CP-net learning techniques is to learn (i.e. rebuild) a CP-net that can describe the whole data-set[ref]. However, since the $S$ is not usually clean,   there is no possibility of finding such a CP-net, that is consistent with every example in $S$. This fact motivated us to frame the CP-net learning problem as an optimization problem that is, to identify a model that maximizes some objective function, $f$, with respect to choice data-set. In this work, we utilized the power of Genetic Algorithm (GA) as an optimization technique. GA is an optimization algorithm inspired from the mechanism of natural selection and natural genetics, which can work without any a-priori knowledge about the problem domain and have received a growing interest in solving the complex combinatorial optimization problems especially for their scalability as compared with the deterministic algorithms [1]. In this work, we investigate the feasibility of implementing the GA to solve the passive CP-net learning problem.

The Concepts of Leadership Theories

This essay begins with how the concept of leadership starts with understanding what leadership means. According to Robbins and Judge, Organizational Behaviour, 15th edition states that leadership is the ability to influence a group towards the achievement of a vision or set of goals (p, 402). A good leader is more likely to accomplish this task through knowledge and skill.Knowledge to know about how to use what is known to influence workers in an organization to reach the goals of a company and skill to put in the effort to actually do what is meant to be done well to achieve organizational goals. In other words an effective leader should be capable of inspiring and motivating even the most inefficient employees to strive towards attaining the goals of the organization. Organizational effectiveness is critical to success in any business.In order to achieve increased and sustainable business results, organizations need to execute strategy an engage employees. T he validity of the stat ement ‘’an organisations performance and effectiveness are directly related to its leadership,† can be further explained by drawing a little focus on the theories of leadership. These theories include situational theory, participative leadership model, the path-goal theory and the transformational leadership theory. Situational theories focus on the followers.Situational theories propose that the effectiveness of a particular style of leadership is dependent on the context in which it is being exercised. For example, in a situation where the leader is the most knowledgeable an experienced member of a group, an authoritarian style might be most appropriate but in other instances where group members are skilled experts, a democratic style would be more effective. Fieders situational theories identify effective leadership style under changing situations (Fieder, Chemers and Mahon, 1977). These can be either relationship motivated or task motivated.A leader participat ive model is a leadership theory that provides a set of rules to determine the form and amount of participative decision making in different situations. These leaders encourage participation and contribution from groups members and helps members feel more relevant and committed to the decision making process. Persons are less competitive and more collaborative when they are working on joint goals. It has been proven that when decisions are made together, the social commitment to one another is greater and increases the commitment to he decision rather than when decisions are made by one person alone. Participative leadership can be effective in unstructured situations because it can increase role clarity and it can also be very effective for people who have a high need to control their environment. The path-goal theory which was developed by Robert House is a theory that states that it is a leader’s job to assist followers in attaining their goals and to provide the necessary direction and support to ensure that their goals are compatible with the overall objectives of the group or organization. Robbins and Judge 15th Edition) Effective path-goal leaders must recognize the needs of those they manage and try to satisfy their needs through the workplace by rewarding persons for achieving their goals, helping subordinates to identify the most effective path they need to take to reach their goals and clear the paths so that these subordinates can reach their goals. The transformational leadership theory focuses on the connections formed between leaders and followers.Transformational leadership is a process in which the leaders take actions to try to increase their associates' awareness of what is right and important, to raise their associates' motivational maturity and to move their associates to go beyond the associates' own self-interests for the good of the group, the organization, or society. Such leaders provide their associates with a sense of purpose that goes beyond a simple exchange of rewards for effort provided. The transformational leaders are proactive in many different and unique ways.These leaders attempt to optimize development, not just performance. Development encompasses the maturation of ability, motivation, attitudes, and values. Such leaders want to elevate the maturity level of the needs of their associates (from security needs to needs for achievement and self-development). They convince their associates to strive for a higher level of achievement as well as higher levels of moral and ethical standards. Through the development of their associates, they optimize the development of their organization as well.High performing associates build high performing organizations. A transformational leadership is more effective when in a smaller, privately held firm than in a complex organization because the personal nature can directly interact with the workforce and make decisions than when they report to an external bro ad of directors or deal with a complex bureaucratic structure. I conclude that each of these theories offers some insights into the qualities of successful leaders.The different leadership styles will differ depending on the type of organizational structure being used but they are all important for the effectiveness and performance of any organization. Bibliography Bass, B. M. (2005). Transformational leadership theory, In J. B. Miner. Organizational behavior Fiedler, (1967) A Theory of Leadership Effectiveness. NewYork: McGraw-Hill. Langton, N. , ; Robbins, S. (2007). Leadership. In N. Langton ; S. Robbins. Organizational Behavior: Concepts, controversies, applications Toronto: Prentice Hall Canada

The Downside Risk of Ielts Essay Writing Samples for General Training That No One Is Talking About

The Downside Risk of Ielts Essay Writing Samples for General Training That No One Is Talking About A well-structured essay has a fantastic introduction, body paragraphs that are simple to follow and connect with each other, and a great conclusion. Below are examples of the 3 distinct varieties of letters. To take a very simple example, if you're writing about the pros and cons of something, you might wish to have one paragraph about each. Thus, the prior instance is a personal letter. In Task 1, test takers are requested to respond to a circumstance, by writing a letter as an example, requesting information or explaining a scenario. The very first thing you have to do is recognize what kind of letter the question demands you to write. Your very first job, before you get started writing, is to determine which kind of letter you must write by identifying the task given. The letter opening and signing off statement differ depending on the manner of letter you're writing. But What About Ielts Essay Writing Samples for General Training? If you're writing about something that happened in earlier times your verbs should be in the previous tenses. The points aren't always linked together well and punctuation may be faulty. Lots of people are concerned about their grammar but, as it is possible to see, grammar is just one section of four used to grade your writing. If you're weak at English grammar, attempt to use short sentences. Our sample essay has a very simple but great introduction in which it demonstrates that the examinee has knowledge of the subject and clearly states the writer's position to prepare the remainder of the essay. PaperCoach can assist you with all your papers, so take a look at the moment! I would be pleased to assist you prepare for the writing test. Things You Won't Like About Ielts Essay Writing Samples for General Training and Things You Will You also desire a mixture of cohesive devices. If you're arranging something later on, you'll need to use the future tenses. More You may be lucky and have some overall knowledge or expertise about the question you're given. However, there are lots of issues with this arrangement and you find it rather hard to get the job done. It is very important to read and understand the question, in addition to follow the directions carefully. There's a lesson here that explains the significance of identifying the task to be sure you fully answer all areas of the question. At length, there aren't any appropriate answers or methods. Have a peek at these sample questions. Choosing Ielts Essay Writing Samples for General Training The direction you organize your ideas will certainly impact your score. Certainly, money has an important role in our lives. Certainly, it is an important part in our lives. You also have to have an obvious position throughout. Many crimes are being committed by men and women in need that are made to take the things that they do not have and by people hooked on drugs. It's hard for any persons to accept a partner who doesn't have money or no less than a job to care for their upcoming family. It's hard for any persons to accept a partner that does not have money or no less than a job t o deal with future family. The Hidden Truth About Ielts Essay Writing Samples for General Training Increasing the availability and application of public transportation and increasing using renewable energy sources could lessen world pollution further. Solving these problems is not simple. Explore the benefits of both methods and provide your own opinion. You must have frequent error-free sentences. You will have to show you can use a wide array of sentence structures and have a high amount of accuracy. The reach of grammatical constructions used seems quite excellent. Also make sure you use an assortment of different sentence structures in order to have a high score.

Animal Shelter Reflection Essay - 1063 Words

There is a Pedigree dog commercial I see on television which catches my eye and my heart. It tells us to not pity a shelter animal. When I decided to become a Veterinary Technician, I anticipated working in a vet office. Unpredictably, I changed my mind. Approximately a year ago, I began volunteering for the Denver Dumb Friends League at the Buddy Center in Castle Rock. A shelter is not always the easiest place to work. Nevertheless, I feel it is where I feel most able to make a difference. There is plenty of heartache, but I seem to have a knack for calming and comforting the frightened animals, and that makes me feel good. My volunteer role involves helping with surgery, giving animals their medicine and processing incoming animals. In†¦show more content†¦I get to speak with groups of children and adults about animal needs, safely approaching a strange animal and overcrowding. It is extremely important to educate people about the need to have animals spayed/neutered. I se e so many animals unable to find homes because the majority of people see adorable babies and overlook the adults. An effective technique to teach about overpopulation is through stuffed animal kittens. When we visually show how quickly they can multiply, it is easy for people to see why we need to control animal reproduction. When properly cared for, many animals live a long and contented life. Cats can live up to twenty years old, so adopting one who is ten is not too old. I enjoy giving people tours of the Buddy Center and educating about services the shelter offers. In addition to showing what animals need to keep them healthy and happy, we explain how to relinquish an animal. Sometimes tours involve showing animals available for adoption. I love to help with adoptions because people are excited to get a new family member. It is a pleasure to see them walk out of the shelter full of smiles with a clearly delighted animal going home. In spite of all the positives, there are some negative aspects to working in a shelter. It is difficult when animals are scared, and I am unable to help them feel better. Sometimes, animals arrive who have been on the streets and they are in bad physical shape.Show MoreRelatedThe Problem Of Pet Adoptions940 Words   |  4 Pagesrecent advertisement by The Shelter Pet Project suggests. By tugging, I’m referring the to the â€Å"heart strings† of the audience. The ad features a somewhat large, orange cat looking into a bathroom mirror. Nothing too peculiar about that image right? Wrong. The text of the ad, ‘Does this fur make me look fat?’ is within a cloud shaped thought bubble followed by the claim ‘There’s nothing wrong with shelter pets.’ Joined with the uncertainty and sadness of the cat’s reflection; the ad depends heavily onRead MoreIntegration Of Your Community Service Experience With Psychological Theory And Concepts942 Words   |  4 Pagesgroup without noticing th e psychological theories behind the services. Suncoast Animal League primarily utilizes ideas from Maslow’s Hierarchy as well B. F. Skinner’s theory of operant conditioning. When observing the volunteers that work there, including myself, motivational theories give some insight to the internal reasons to serve. Initially, simply by observing the care Suncoast Animal League provides the animals, Maslow’s Hierarchy can certainly be applied. 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Dogs were working dogs earning their keep on a local ranch or farm, or they were used for hunting to help put food on the table. Some dogs, as well as cats, wereRead MoreEssay Animal Control715 Words   |  3 Pages The Maricopa County animal control has evolved over the last century and the best way to understand animal control is to look at it through history. nbsp;nbsp;nbsp;nbsp;nbsp;During the first quarter of the 20th Century, Maricopa County communities were rural and sparsely populated. Dogs and cats were valued for what they contributed to this rural lifestyle. Dogs were working dogs earning their keep on a local ranch or farm, or they were used for hunting to help put food on the table. Some dogsRead MoreEdmond Burke Vs Rousseau1090 Words   |  5 Pagesmust first strip him of everything that makes him who he is, and imagine what he would be like in the state of nature (Rousseau, 26,). According to Rousseau, in the state of nature, man is a solitary, asocial animal whose only concern is satisfying primal needs. If man has food, water, shelter, and sleep man needs nothing else: â€Å"I see him eating his fill under an oak tree, quenching his thirst at the first stream, making his bed at the base of the same tree that supplied his meal, and, behold, hisRead MoreThe World Of The 21st Century And The Current State Of Humanity1039 Words   |  5 PagesBiological factors such as an up-right posture, humans and animals are totally different. It is because humans are created in the way that they are given the free will of choice; a choice to do whatever they want/need to. This resulted to a new dimension of behavior that is seen in humans as to animals. There is a great debate on whether humans and animals are alike in terms in the existence of a presence of a soul (person) in that body(human or animal). Many agree that it is because of the presence ofRead MoreMy Views on Animal Rights1718 Words   |  7 Pagesthat I found most interesting is about animal rights. I want to further express my view on this topic. I believe animals do not have rights and people only give animals rights because people believe animals have souls. I have come to this conclusion due to further reading and personal experience. Animals do not have rights because animals do not have voices. If animals had voices they would be considered human beings, which of course, they are not. Animals are actually sub-creatures of the worldRead MoreMeat the Truth: The Humane Problem750 Words   |  3 PagesThe world has different views on whether it is ethical to eat meat. The most important moral should be that the animals are being treated humanely before and during the slaughtering process. Customers who eat meat need to know that the meat they are buying does not come from mistreated animals. Customers should be buying their meat from small farms or larger companies that promote cruelty-free production. Broiler chickens are kept to a point they can barely walk and hens are piled in a small cageRead MoreMedia Bias And The Media980 Words   |  4 Pageswith such a continuous stream of standardized opinion, bourne along upon an equally inexhaustible flood of news and sensation, collected from every part of the world e very hour of the day, that there is neither the need nor the leisure for personal reflection. All this is but part of a tremendous educating process. It is an education at once universal and superficial. It produces enormous numbers of standardized citizens, all equipped with regulation opinions, prejudices and sentiments according to their

Fall Of The Roman Empire Essay - 1464 Words

FALL OF THE ROMAN EMPIRE: Jesse R. Allen HIST 115 12/11/2016 Rome, once a city-state with conquests on Asia-Minor, Afria, Corsica, Spain, and Sarinina had become a ruling empire in the Mediterranean by 150BCE (Ridley, The Fall of the Roman Republic 2016). This dominant empire remained on power for many centuries and came to an end in a few mere decades. By the turn of the 5th century, the western empire, functionality of this empire had ceased to work while its eastern counterpart continued for almost another thousand years. This collapse affected trade network and communication routes. Scholars have several conclusions on the cause of this failure, but only a few prevail to be a main cause of this demise. Economics played a huge part in the collapse. Estate owners and commercial farms extensively used slave labor and concentrated on lucrative crop production such as grapes and olives for exports (Morato 2016). Cheap labor gave these large estates cost advantages over smaller lands which had to rely on work done by its owners. Slaves gave estates additional benefits as they were tenant labor which means they could be worked longer and harder than non slaves. In the first century, there were a substantial number of non-slave laborers working the land. Over time, there was a consolidation of small farms as owners had to sell or went off to assist in war efforts. Pastures once used for the production of grains were converted to vineyards and orchards. ThisShow MoreRelatedFall of the Roman Empire1288 Words   |  6 PagesThe Pax Romana was a two hundred year time period where the Romans had peace and prosperity under Augustus. The Roman empire started to decline at the end of the prevail of the last five emperors, Marcus Aurelius in 161-180 A.D. The rulers in the next century had no idea how to deal with the problems the empire was having. 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Augustus Caesar was the first emperor. He created harmony in Rome, but not in calendars as he added August as the eighth month to follow July, which was named afterRead MoreFall of Roman Empire1175 Words   |  5 PagesThe Fall of the Roman Empire The Ancient Roman empire was one of the most prominent and successful societies of its time period. By the end of their reign, the Romans had conquered almost all of the Mediterranean including parts of present day Europe, Asia, and Africa. Rome was at its strongest during the rule of Augustus Caesar, this time was known as the â€Å"Pax Romana† or Roman peace. It wasn’t until later, when Emperor Trajan took over in about 98 C.E. that the Empire reached its peak. AfterRead MoreThe Fall of the Roman Empire609 Words   |  3 PagesThe Fall of the Roman Empire There are adherents to single factors, but more people think Rome fell because of a combination of such factors as Christianity, and economy, and military problems. Even the rise of Islam is proposed as the reason for Romes fall, by some who think the Fall of Rome happened at Constantinople in the 15th Century. Most people think it occurred during the fifth century, after the western division of the empire. There were several reasons for the fall of the Roman EmpireRead MoreThe Fall Of The Roman Empire1438 Words   |  6 PagesThe Roman Empire was one of the most powerful empires in the history of mankind. In 476 CE Odoacer defeated Romulus Augustus to capture Rome; most historians agree that this was the official end of the Western Roman Empire. There is much debate on how exactly Rome declined and eventually fell. The fall of Rome was a long process that took place over many centuries. There are five main schools of thought on why Rome fell. First, Christianity, offered by Edward Gibbons; He suggests that ChristianityRead MoreThe Fall Of The Roman Empire1495 Words   |  6 PagesFor a long period of time, the debate about the cause of the fall of the Roman Empire has been a popular topic amongst historians. Most of these historians look at the issue from a standpoint that accepts that there were most likely several causes. The main root of the issue is whether or not these causes were internal or external. Some historians even go more in depth and try to hypothesize what the internal or external causes were. In fact, Adrian Goldsworthy and Peter Heather do just this when

Cancer Diary of Osteosarcoma Free Essays

SUBMITTED BY: ARAGAW GEBEYEHU SUBMITTED: DR. FLORES ROZAS DATE OF SUBMISSION: 04/16/1801/26/12 My name is osteosarcoma. I am highly malignant tumor of mesenchymal origin and the second most common primary malignant bone tumor . We will write a custom essay sample on Cancer Diary of Osteosarcoma or any similar topic only for you Order Now I am originate from mesenchymal cells. I have spindle shape and hyper chromatic nucleus. I have been formed when osteoblasts cells secreted malignant osteoid. I am like osteoblast (bone forming) cells, but I cannot make strong matrix like them. You know that osteoblasts originate from immature mesenchymal stem cells. So my ancestors are from those. But I am already modified in to osteosarcoma cell. I can occur at any bones found in the body. I am more frequent at sites of the most rapid bone growth; those are extremities of long bones near metaphyseal growth plates. From the sites that I frequently choose ;distal and proximal end of femur (42%),proximal end of tibia(19%), proximal end of humerus (10%), pelvis skull and jaw(85%) and pelvis( 8%). I can be appearing 1 to 3 million people per year. Off course, I am rare compared to other types of cancer. I can attack any age as primary osteosarcoma but mostly between 10-25yrs. I can also come at older individuals as secondary osteosarcoma. I affect males little bit more than females. I am most common in patients with Fraumeni syndrome, Rothmund-Thomson syndrome, Bloom and Werner syndromes. Exposing to Paget disease and ionizing radiation give favorable conditions for me to develop our colony. Fig 1. Osteosarcoma genesis and osteogenesis When I was changing to osteosarcoma, there was a mutations of MDM2 amplifications which led to p53 gene inactivation. Another controller gen which is called retinoblastoma (RB) genes was also altered. I become safe because there is no more check point and control for me .But the normal bone cells have several check points in their cell cycle. In the presence of RB mutations I will occur at an incidence 500 times that of the normal population. Normal cells are always worrying for G1/S check point but I am not, because the p53 and Rb genes are already mutated (lost their function). I am preparing more DNA and for that I am also synthesizing mRNA and important proteins. During my replication time I gained chromosome number 1 and lost chromosome 9, 10 and 13. Till now I am successfully dividing and I am forming other similar cells. In near future I will have my own colony of cells and my own sarcoma tissues01//14/2014As usual I was preparing to divide but the proteins detected a damage in my DNA. The damage was too big to be repaired. Even if it is bigger damage I will not go to programmed cell death called apoptosis. Because this is not my character. My only goal is to survive and proliferate more. This is my unique behavior. Of course I was not like this, I was following the normal path of cell cycle and programed cell death. This thing happened after I lost my DNA sequence that triggers cell death pathway.5/18/15Recently I got another mutations and my FOS and Jun proteins are up regulated. Those proteins are components of activator protein1 complex (AP-1). AP-1 his regulator of cell transcription. Now I am getting additional energy because my transcription regulators are out of service. I can proliferate freely and destroy bone cortex and extend towards bone marrow cavity and soon out wards towards adjacent soft tissues.10/17/15I am now thinking why not I visit other organs. I have information lung, liver and also other bones are the safe place and more fertile to me . When I become more organize, I can migrate and live there. I am already resistant to programed cell death (anoikis) and can exhibit anchorage independent growth (AIG). Abnormal integrin? v6, Rho, ATPase e.g. Racl and Cdc42 upregulated p13 kinases which in turn inhibited proapoptotic factor Bad and this protected me from apoptosis even when I am not attached to any membrane. Now I have bigger size with hypoxic and acidic environment. So I need supporting blood vessels to obtain oxygen and nutrients I have done angiogenesis for my sustained growth and further metastasis. My intrinsic conditions have to lead to stimulation of von Hippie Lindau protein. It releases hypoxia inducible factor-1? (HIF-?)which further up regulates several VEGF gene such as VEGF A through VEGF E. This further releases Nitric oxide (NO) from endothelial cells and results in vasodilation and increased vascular permeability. By doing those processes I got leaky and irregular vasculature.3/14/16 I am starting flight to lung. I am using integrin proteins, which found in my surface ,in attaching to matrix proteins (fibronectin).For my signal transduction and interaction with other cells, I use integrin along with ezrin protein ,foal adhesion kinase (FAK),protein kinase C (PKC) and Rho GTPase. They also help me for my conformational changes. Besides to this matrix metalloproteinase (MMPs) are helping me in my sojourn through blood vessels and tissue renewal process. Now I have reached the lungs and I am growing, multiplying and consuming all nutrients. It is like as I heard .I like it.10/10/2016Today, the patient could not resist me .He took me to hospital. Because I create sever pain and swelling. I was diagnosed by radiograph as high grade sarcoma. Additionally they did CT scan, RI and biopsy and confirmed my stage. They are now discussing to fight against me.Yes they have started chemotherapy (high dose methotrexate, doxorubicin and cisplatin). I have been fighting against those drugs for the last three months and I am now getting old, starving and feeling weaker day by day. Oh those drugs become treble for me. Methotrexate is a dihydrofolate reductase inhibitor, it can block folic acid supply which is needed for my RNA and DNA synthesis. Doxorubicin which is also a drug that interact with my DNA and inhibits biosynthesis of macro molecules. Cisplatin causes damage to my DNA. I have to create solutions, because I am no longer able to make RNA efficiently. But I am struggling to continue my life. I got another mutations which is alteration in reduced folate reductase (RFC) protein Leu291pro.Yes I did it. This alteration unable carrier to transport methotrexate towards me .Besides to this, membrane pump-glycoproteins (P-gp) is also helping me with pumping out these drugs. Due to this I start dividing and spreading slowly but steadily. Other worse situations are happening to me, they are using high energy rays (x-rays) to kill me. I am no longer able to grow. I am shrinking. 4/14/18The worst thing are happened on me. Now, they are performing surgery and removing me as cancerous tissue. I was sending my daughters to afar to lung. By myself I am highly depressed and weak due to huge loss my colony. I try to grow and spread again by my reserve soldiers and by those immigrant members. They are still in dilemma to administer chemotherapeutic agent after surgery. The people are always struggling to combat me and other friends. If they post-surgery chemotherapy no more survival .I say good bye I will not be there anymore. REFERENCE Biomarkers in osteosarcoma, Colin Kong, M.S and Marc F. Hansen, Ph.D.Biology and therapeutic advances in pediatric osteosarcoma, Nayssa Marina Et.al,The oncologist ,2003 Novel therapeutic strategy for osteosarcoma targeting osteoclast differenciation, bone reabsorbing activity ,and apoptosis pathways.The molecular pathogenesis of Osteosarcoma; A review, Matthew L. broadhead, sarcoma, 2011. Current strategy for chemotherapy in Osteosarcoma, Dorothy carric, International Orthopedics, 2006 Osteosarcoma: A review of diagnosis ,management and treatment strategies, David S. geller ,MD, and Richard Gorlic MDSwitch from ?v?5 to ?v?6 integrin expression protects squamous cell carcinomas from anoikis, S.M. Janes ,Journal of cell Biology,2006. Analysis of molecular mechanisms of osteosarcoma using bioinformatics approach ,Jaxon yang ,oncology letters,2016. How to cite Cancer Diary of Osteosarcoma, Papers

Customer and Employee Experience Response-myassignmenthelp.com

Question: Differences between Customer and Employee Experience? Answer: Introduction The customer experience refers to the response which a customer develops either internally or externally towards the product and the services received in a given organization by either the customer service or selling staff. The physical interaction, for the most part, occurs during the time of procuring the product, utilization, and the benefit accruing(Chang Lin, 2015). Aberrant contact in most cases involves the rapid experiences which depicts the companys products, quality of management, and the branding. The employees work towards fulfilling the promises made to their customers. There quite distinct differences that emerge out of the duos. The customer experience as it got stated above involves the internal and the external response of the customer towards the products or the services offered by an organization. The customer experience may be the perception that the product produced by a specific firm is of high quality and standard or may perceive the product offered is of low quality and overpriced. Dependent on the perception, the customer is the essential tool for a firm to use in the benchmarking the services and products it offers(srivastava Kaul, 2014). Based on the survey conducted by the business on the customer response, the company would work towards improving on the areas of weakness and improve on the products and services that the customer gave a positive response. On the other hand, employee experience includes the perception that the staff of an organization towards what has just happened or about to happen. In the business field, such a per ception may get to be on how a certain product gets developed successfully and how the customer positively recommended on its quality(Farndale Kelliher, 2013). Furthermore, the employee experience would give a view on how the customer got handled in the process of purchasing the companys products. For any staff working for a firm needs to consider the customers as the priority employers and deliver the very best. In some cases, the experience for both the customer and the employee may get to be positive or negative under varying conditions. For example, there would be circumstances for the customer to perceive the reception and the quality of customer of a given as warm since she/he received the necessary attention and the problems solved passionately. The negative side of the customer experiences emerges that time he/she gets inadequate attention and arrogantly answered by the firms staff meant to serve him or her(Walker, et al., 2014). On the other hand, the employee may turn to be positive in situations where he/she receives appreciation for the good work done even without the monetary award but just appraisals. When a junior employee gets appraisals from the company management, he gets motivated and works towards achieving more for the firm. However, in those circumstances that the employee develops negative experience might be out of lack of recognition of his/her efforts in the progress of the company. Finally, the customer experience may make the firm to grow and progress through talking positively about the products and the services offered by the firm. Through such customer satisfaction acts up to the extent of marketing the company amongst their friends would attract more customers(Dabholkar, 2015). Thus, the firm would expand. Meanwhile, the employee experience gets to determine whether the enterprise succeeds or fails through the staff efforts. Employee and Customer Experience Interaction with the Organization Capabilities and Processes The capabilities include all the collective abilities, the skills and the expertise within an organization. Usually, the capabilities are as a result of the productive investments in the staffing, the training, the compensation, the communication and the other artificial resources. The firm processes include the production, marketing, refining, and others(Camison Villar-Lopez, 2014). The employee and customer experiences interact with the mentioned capabilities for example through the effective communication skills between an employee and his/her supervisor, between the customer care and the customer, builds a positive image and creates a positive experience for the duos. Further, the firms expertise, abilities, and the skills would bridge the gap between the experience of the employee and the customer in the process of working for the enterprise or buying its products. Conclusion It is evident that for the company to grow and progress the experience of both employee and customer should always be positive. With the positive perception of the customer about the products and services provided by a given firm helps to brand the reputation of the organization and the customer moves around informing the friends and family members about the company. Such an act brands the company positively. Finally, a motivated employee would work towards achieving more for the firm he/she works for, hence, promoting the growth of the business. References Camisn, C. and Villar-Lpez, A., 2014. Organizational innovation as an enabler of technological innovation capabilities and firm performance.Journal of Business Research,67(1), pp.2891-2902. Chang, S.H. and Lin, R., 2015. Building a total customer experience model: Applications for the travel experiences in Taiwans creative life industry.Journal of Travel Tourism Marketing,32(4), pp.438-453. Dabholkar, P.A., 2015. How to improve perceived service quality by increasing customer participation. InProceedings of the 1990 Academy of Marketing Science (AMS) Annual Conference(pp. 483-487). Springer International Publishing. Farndale, E. and Kelliher, C., 2013. Implementing performance appraisal: Exploring the employee experience.Human Resource Management,52(6), pp.879-897. Srivastava, M. and Kaul, D., 2014. Social interaction, convenience and customer satisfaction: The mediating effect of customer experience.Journal of Retailing and Consumer Services,21(6), pp.1028-1037. Walker, D.D., van Jaarsveld, D.D. and Skarlicki, D.P., 2014. Exploring the effects of individual customer incivility encounters on employee incivility: The moderating roles of entity (in) civility and negative affectivity.Journal of Applied Psychology,99(1), p.151.